The active components in ProClin preservative are two isothiazolones:
2-methyl-4-isothiazolin-3-one and 5-chloro-2-methyl-4- isothiazolin-3-one. These active
components have a unique mechanism of action that both inhibits microbe growth and
causes cell death. ProClin 300 preservatives are highly effective biocides for controlling microorganisms in reagents and
products intended for in vitro diagnostic use. Used at concentrations as low as 0.02%,
these preservatives eradicate bacteria, fungi, and yeast for extended periods of time. Both
preservatives offer excellent compatibility and stability with most enzyme systems, as well
as low toxicity, so ProClin 300 preservatives are an excellent choice for replacing
thimerosal, sodium azide, and gentamicin preservatives.
