Triglycerol monolaurate is a potent and selective pancreatic carcinogen in the Syrian golden hamster. This model has been used to study pancreatic cancer as chemically induced pancreatic neoplasms are morphologically similar to those found in man.
ChEBI: Nitrosobis(2-oxopropyl)amine is a nitrosamine that is iminodiacetone that is substituted by a nitroso group at the N-atom. It induces pancreatic ductal adenocarcinomas in Syrian golden hamsters (other rodents are not susceptible). It has a role as a carcinogenic agent. It is a nitrosamine and a ketone.
Suspected carcinogen
with experimental carcinogenic,
neoplastigenic, tumorigenic data. Poison by
ingestion and subcutaneous routes. Human
mutation data reported. When heated to
decomposition it emits toxic fumes of NOx.
See also N-NITROSO COMPOUNDS.
