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Glucose-13C6

Product NameGlucose-13C6
CAS110187-42-3
MFC6H12O6
MW186.11
EINECS
MOL File110187-42-3.mol

Chemical Properties

Melting point	150-152 °C(lit.)
Density	1.581±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp.	Refrigerator
solubility	Methanol (Slightly, Heated, Sonicated), Water (Sparingly, Sonicated)
form	Solid
color	White to Off-White
optical activity	[α]25/D +52.0°, c = 2 in H2O (trace NH4OH)
InChI	InChI=1/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6/s3/i1+1,2+1,3+1,4+1,5+1,6+1
InChIKey	WQZGKKKJIJFFOK-NYKRWLDMSA-N
SMILES	[13C@H]1([13CH2]O)O[13CH]([13C@H](O)[13C@@H](O)[13C@@H]1O)O \|&1:0,5,7,9,r\|
CAS Number Unlabeled	50-99-7

Safety Information

WGK Germany	3
HS Code	2845909090
Storage Class	11 - Combustible Solids

MSDS

Provider	Language
SigmaAldrich	English

Usage And Synthesis

Chemical Properties

White Solid

Uses

D-Glucose-¹³C₆ has been used:

for de novo fatty acid (FA) synthesis
as a component in tracing media for the analysis of stable isotope tracer
in minimal media for recombinant protein production
for cell suspension

Uses

Glucose-13C6 is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus.

Uses

Glucose-13C6 can be used in enzymic synthesis of cyclohexyl-α and β-D-glucosides

Biochem/physiol Actions

D-Glucose-13C6 functions as a tracer and helps to access glucose kinetics in vivo.

in vivo

D-Glucose-¹³C₆ (0.1 g in 25 g carrot medium for eggs or incorporated with 1 g of 99.5% sucrose in 15 mL water for adults) lightly decreases egg hatching rates, larval development, emerged adults, the period and the number of mating in Ceratitis capitata^[1].

Animal Model:	Ceratitis capitata^[1]
Dosage:	0.1 g
Administration:	Add into 25 g carrot medium for eggs or incorporated with 1 g of 99.5% sucrose in 15 mL water for adults
Result:	Decreased hatching rate from 85% to 79% and number of emerged adults from 57% to 50.6%, prolonged development time. Decreased the number and period of mating lightly for larvae labeled flies, while decreased the period of mating a bit more for adult labeled flies.

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