3-HYDROXY-3-PHENYL-PROPIONITRILE

Product Name3-HYDROXY-3-PHENYL-PROPIONITRILE
CAS17190-29-3
MFC9H9NO
MW147.17
EINECS
MOL File17190-29-3.mol

Chemical Properties

Boiling point	306-307 °C (lit.)
Density	1.112 g/mL at 25 °C (lit.)
refractive index	n20/D 1.5420(lit.)
Flash point	>230 °F
storage temp.	Sealed in dry,2-8°C
solubility	soluble in Chloroform, Dichloromethane, Ethyl Acetate
pka	13.00±0.20(Predicted)
form	liquid
color	Colourless

Safety Information

WGK Germany	3
HS Code	2926907090

MSDS

Provider	Language
SigmaAldrich	English

Usage And Synthesis

Chemical Properties

Orange Oil

Uses

3-Phenyl-3-hydroxypropanenitrile (cas# 17190-29-3) is a compound useful in organic synthesis.

Definition

ChEBI: 3-hydroxy-3-phenylpropionitrile is a nitrile that is 3-phenylpropionitrile in which one of the methylene hydrogens at position 3 is replaced by a hydroxy group. It is a nitrile, a member of benzyl alcohols and a secondary alcohol. It is functionally related to a 3-phenylpropionitrile.

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 366, 1983 DOI: 10.1021/jo00151a017
Synthetic Communications, 24, p. 1433, 1994 DOI: 10.1080/00397919408011747
Tetrahedron Letters, 26, p. 155, 1985 DOI: 10.1016/S0040-4039(00)61867-1

General Description

3-Hydroxy-3-phenylpropionitrile, a β-hydroxynitrile, is an aryl substituted α-aminophenylaceronitrile. It can be obtained by reacting lithioacetonitrile with benzaldehyde via asymmetric 1,2-addition reaction.