Methyltetrazine-DBCO is a TCO reactive reagent containing a methyltetrazine group and a DBCO moiety. DBCO is commonly used for copper-free Click Chemistry reactions.
Biological Activity
Methyltetrazine-DBCO is a non-cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.