1-?[[4''-?(Cyclopropylmethyl)?-?2-?(4-?pyridinylamino)?[4,?5''-?bipyrimidin]?-?2''-?yl]?amino]?-?2-?methyl-2-?propanol is a selective PI 3-?kinase VPS34 inhibitor. VPS34 inhibitors can be used to investigate autophagy, a degradation process that recycles cellular components.