Fluticasone is an inhaled corticosteroid used in the treatment of respiratory diseases.
therapeutic for asthma and allergic rhinitis Flonase
ChEBI: A trifluorinated corticosteroid used in the form of its propionate ester for treatment of allergic rhinitis.
Cutivate (Altana); Flonase (GlaxoSmithKline); Flovent (GlaxoSmithKline).
Fluticasone (1 mg/kg; intranasal dropping; 7 d) suppresses rhinovirus-induced airways inflammation in vivo but also impairs anti-viral immune responses and increases viral titres, leading to mucus hypersecretion[4].
| Animal Model: | C57BL/6 mice[4] |
| Dosage: | 1 mg/kg |
| Administration: | Intranasal dropping; 1 h before infection with rhinovirus 1B; 7 days |
| Result: | Suppressed BAL neutrophil numbers and inhibited rhinovirus-induced airway inflammation. |
