JWH 073 is a synthetic cannabinoid (CB) that activates both the CB
1 and the CB
2 receptor (K
i = 8.9 and 38 nM, respectively).
1 This cannabimimetic compound has been identified in herbal blends.
2,3,4 JWH 073 2-
methylnaphthyl analog differs structurally from JWH 073 by having a methyl group added at the 2 position of the naphthyl moiety. The biological and toxicological properties of this compound have not been characterized. This compound is intended for forensic and research purposes.
1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2),133-140(2000).
2. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan Leg. Med. (Tokyo) 13(3),109-115(2011).
3. Lindigkeit, R., Boehme, A., Eiserloh, I., et al. Spice: A never ending story Forensic Sci. Int. 191(1-3),58-63(2009).
4. Uchiyama, N., Kikura-Hanajiri, R., Ogata, J., et al. Chemical analysis of synthetic cannabinoids as designer drugs in herbal products Forensic Sci. Int. 198,31-38(2010).
