CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPARα and PPARγ with EC50 values of 0.173 and 0.642 μM, respectively.1
References
1. Caijo, F., Mosset, P., Grée, R., et al. Synthesis of aromatic analogs of 8(S)-HETE and their biological evaluation as activators of the PPAR nuclear receptors J. Org. Chem. 2006(9),2181-2196(2006).
