Description
CAY10514 is an aromatic analog of 8(S)-
HETE. It acts as a dual agonist of PPARα and PPARγ with EC
50 values of 0.173 and 0.642 μM, respectively.
1
Uses
CAY10514 is an aromatic of 8(S)-HETE. CAY10514 acts as a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ with IC50 of 0.173 and 0.642 μM, respectively[1].
References
1. Caijo, F., Mosset, P., Grée, R., et al.
Synthesis of aromatic analogs of 8(S)-HETE and their biological evaluation as activators of the PPAR nuclear receptors J. Org. Chem. 2006(9),2181-2196(2006).
