Ai3-21201

(-)-Sesamin isolated from Asarum forbesii Maxim, is an isomer of Sesamin. Sesamin is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis[1][2].

[1] Feng Zhang, et al. A new amide from Asarum forbesii Maxim. J Asian Nat Prod Res. 2005 Feb;7(1):1-5. DOI:10.1080/10286020310001596015
[2] Cheng FC, et al. Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. Int J Biomed Sci. 2006 Sep;2(3):284-8. PMID:23674992