ChemicalBook Product Catalog Biochemical Engineering Inhibitors Cell Cycle Rho inhibitor CCG-1423

CCG-1423

Chemical Properties

storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	DMSO: soluble5mg/mL, clear (warmed)
form	White solid
color	white to beige
InChI	1S/C18H13ClF6N2O3/c1-9(15(28)26-14-4-2-13(19)3-5-14)30-27-16(29)10-6-11(17(20,21)22)8-12(7-10)18(23,24)25/h2-9H,1H3,(H,26,28)(H,27,29)
InChIKey	DSMXVSGJIDFLKP-UHFFFAOYSA-N
SMILES	FC(F)(F)c1cc(cc(c1)C(=O)NOC(C)C(=O)Nc2ccc(cc2)Cl)C(F)(F)F

Animal Model:	16-week-old mice with HFD-induced obesity^[1]
Dosage:	0.15 mg/kg
Administration:	Intraperitoneal injection; 0.15 mg/kg once per day; for two weeks
Result:	Improved glucose tolerance and reduced insulin levels at 30 minutes after glucose injection.