Epistane

Epistane (EPI) , also known as Hemapolin or methylepitiostanol, is an orally administered 17α-alkylated testosterone derivative with 2a-3a epithio ring. Epistane is a type of chemical known as an anabolic steroid. It is similar to the hormone testosterone. While Epistane shares some similarities with other prohormones, it is unique in its ability to produce lean muscle gains with minimal side effects.

Epistane is a methylated derivative of the steroid epitiostanol (E588800). Epistane is an readily orally active compound that lacks the 3-ketone common to most anabolic steroids. Epistane greatly incr eases protein synthesis and build up in lean muscle mass.

1. Evaluation of androgenic activity of nutraceutical-derived steroids using mammalian and yeast in vitro androgen bioassays. DOI:10.1021/ac102845y
2. Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuclear receptors in human hepatocytes DOI:10.1007/s00204-019-02643-y