尿苷-5'-二磷酸钠盐
尿苷-5'-二磷酸钠盐 性质
| 储存条件 | -20°C |
|---|---|
| 溶解度 | 在水中的溶解度为100mg/mL，透明，无色至微黄色 |
| 形态 | 粉末 |
| 颜色 | 白色 |
| 水溶解性 | Soluble in water to 100mM |
| 稳定性 | 吸湿性 |
| InChIKey | GFASEGWJDXDCKZ-UHFFFAOYSA-K |
| SMILES | [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)N2C=CC(=O)NC2=O |
尿苷-5'-二磷酸钠盐 用途与合成方法
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Human Endogenous Metabolite
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Uridine 5'-diphosphate sodium salt (100 μM; for 15 min) significantly induces microglial CCL2 and CCL3 mRNA expression.
Uridine 5'-diphosphate sodium salt (100 μM; 3 hours) induces chemokine expression in microglia.
Uridine 5'-diphosphate sodium salt (100 μM; 0.5, 1, 3, 6 12 hours) induces expression of mRNA encoding CCL2 and CCL3 within 30 min, and such expression reaches maximal levels at 1 h, returning to basal levels at 3-12 h.
UDP (10, 100, 1000 μM; 3 hours) induces a concentration-dependent increase in the expression of chemokines at both the mRNA and protein level.
Uridine 5'-diphosphate sodium salt (100 μM; for 15 min) induces activation of NFATc1 and NFATc2 in microglia.
RT-PCR
| Cell Line: | Primary microglia |
| Concentration: | 100 μM |
| Incubation Time: | For 15 min |
| Result: | Significantly induced microglial CCL2 and CCL3 mRNA expression. |
安全信息
| 危险品标志 | Xn |
|---|---|
| 危险类别码 | 22-68/22-68/20/21/22-20/21/22 |
| 安全说明 | 36/37 |
| WGK Germany | 3 |
| 海关编码 | 29349990 |
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 特异性靶器官毒性-一次接触类别2 |
尿苷-5'-二磷酸钠盐 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025-12-22 | HY-W010832 | 尿苷-5'-二磷酸钠盐 | 21931-53-3 | 100mg | 500 |
| 2025-12-22 | HY-W010832 | 尿苷-5'-二磷酸钠盐 | 21931-53-3 | 10mM * 1mLin Water | 550 |
