Anti-CDK8 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25 μg/ml.
Anti-CDK8 Antibody detects endogenous levels of total CDK8 protein.
CDK8 is a regulator of transcription in a multisubunit complex with TFIIH and TEF-β. It exerts positive and negative effects on transcription and is involved signaling th at controls nutrient sensing and cell differentiation. CDK8 phosphorylates the regulatory serine residue of STAT1 and mediates JAK-STAT1 signaling.
