In stomach-lumen-perfused rats and in particular in Heidenhain pouch dogs, S3337 is effective in vivo models and in the H+, K+-ATPase assay[1].
References
[1] Herling AW, et al. A substituted thieno[3.4-d]imidazole versus substituted benzimidazoles as H+, K+-ATPaseinhibitors. Pharmacology. 1988;36(5):289-97. DOI:10.1159/000138397
