Bactobolin hydrochloride (Compound 1) is an antibiotic, which inhibits Escherichia coli, Salmonella, Shigella, Staphylococcus and Bacillus subtilis, with MICs of 0.3-6.25 μg/mL. Bactobolin hydrochloride exhibits antitumor efficacy against leukemia, with a LD50 value of 6.25-12.5 mg/kg[1].
References
[1] Kondo S, et al. A new antitumor antibiotic, bactobolin produced by Pseudomonas. J Antibiot (Tokyo). 1979 Oct;32(10):1069-71. DOI:10.7164/antibiotics.32.1069
