左去氧麻黄碱

中文名称:左去氧麻黄碱
英文名称:D-Methamphetamine
CAS号:537-46-2
分子式:C10H15N
分子量:149.23
EINECS号:208-668-7
Mol文件:537-46-2.mol
左去氧麻黄碱 结构式

左去氧麻黄碱 性质

熔点 143°C (estimate)
沸点 230.33°C (estimate)
密度 0.9285 (estimate)
折射率 1.5105 (estimate)
闪点 9℃
储存条件 2-8°C
酸度系数(pKa) 10.38±0.10(Predicted)

左去氧麻黄碱 用途与合成方法

用途 
食欲抑制剂司来吉克的中间体。

安全信息

危险品标志F,T
危险类别码11-23/24/25-39/23/24/25
安全说明16-36/37-45
危险品运输编号1851
WGK Germany1
危险等级6.1(b)
包装类别III
毒害物质数据537-46-2(Hazardous Substances Data)
毒性A widely abused drug; a sympathomimetic and central stimulant that has been used clinically as an anorectic agent. The use of methamphetamine and related drugs in treating obesity is, however, now generally discredited. It may cause elevation of blood pressure, palpitation, and tachycardia, as well as various CNS effects, including psychotic effects at higher doses. Chronic use of methamphetamine and related compounds, especially at high doses as often occurs with drug abuse, can cause a condition often indistinguishable from schizophrenia. Abrupt withdrawal may cause fatigue, depression, and sleep changes. Methamphetamine is an indirect-acting adrenergic and dopamine agonist that acts principally to release endogenous catecholamines, thereby increasing their synaptic availability. Many of its actions can be blocked by adrenergic and dopamine antagonists. The i.p. LD50 in mice is 70 mg/kg.

左去氧麻黄碱 上下游产品信息