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Telomycin Structure

Telomycin

Chemical Properties

alpha  D28 -133° (c = 1 in 2:1 methanol-water)
Boiling point 850.94°C (rough estimate)
Density  1.1263 (rough estimate)
refractive index  1.6700 (estimate)
storage temp.  Store at -20°C
solubility  DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble; Water: slightly soluble
form  A solid
pka 2.41±0.10(Predicted)
Sequence {Bas}-Ser-Thr-Thr-Ala-Gly-{Pro(3S-OH)}-{Trp(α,β-Didehydro)}-{Trp(β-Me)}-{Leu(3S-OH)}-{Pro(3R-OH)} (lactone bridge: Thr3-Pro11)

Safety Information

Toxicity LD50 in mice (mg/kg): >1000 orally, i.v., i.p., i.m. (Tisch)

Usage And Synthesis

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