AKR1C4 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 323 amino acids (1-323aa ) and having a molecular mass of 37kDa.
Aldo-keto reductase family 1 member C4 or AKR1C4 is a part of the aldo/keto reductase superfamily that has more then 40 known proteins & enzymes. AKR1C4 catalyzes the conversion of aldehydes and ketones to their corresponding alcohols with NADH and/or NADPH as cofactors. AKR1C4 takes place in the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in the liver tissue.
