Cyclic di-AMP (c-di-AMP) is a second messenger produced by bacteria. It impacts bacterial cell growth, cell wall homeostasis, pathogenicity, and other cellular functions.
ChEBI: Cyclic di-AMP is a cyclic purine dinucleotide that is the 3',5'-cyclic dimer of AMP. It has a role as a Mycoplasma genitalium metabolite. It is a cyclic purine dinucleotide and an adenyl ribonucleotide. It is a conjugate acid of a cyclic di-AMP(2-).
c-di-AMP is a bacterial secondary messenger. c-di-AMP acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.