MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
MC-Val-Ala-OH is a cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Protease Cleavable Linker; Cleavable Linker
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:
10.1038/nrd.2016.268