乙氢去甲奎宁
乙氢去甲奎宁 性质
| 熔点 | 123-128° when solvent-free |
|---|---|
| 比旋光度 | D25 -136.2° (alcohol) |
| 沸点 | 476.25°C (rough estimate) |
| 密度 | 1.1027 (rough estimate) |
| 折射率 | 1.6180 (estimate) |
| 储存条件 | 2-8°C |
乙氢去甲奎宁 用途与合成方法
S. pneumoniae
IC50: 25.75 nM (
Plasmodium falciparum
)
ggTas2r1,
ggTas2r2 and ggTas2r7
The mutation rate to Ethylhydrocupreine (Optochin) resistance is estimated using fluctuation analysis in three capsulated S. pneumoniae strains ( S. pneumoniae D39 NCTC 7466, S. pneumoniae R6 ATCC BAA-255 and S. pneumoniae ATCC 49619). The exposure to subinhibitory concentrations of penicillin increased the mutation rate (expressed as mutation per cell division) to Ethylhydrocupreine (Optochin) resistance between 2.1- and 3.1-fold for all three strains studied.
The injection of 1 cc. of a 24 hour dextrose blood broth culture of virulent Type I pneumococci into the right pleural cavity of guinea pigs produces acute suppurative pleuritis on both sides associated with suppurative pericarditis. The injection of 1 cc. of 1:500 solutions of Ethylhydrocupreine hydrochloride into each pleural cavity of guinea pigs at varying intervals up to 24 hours after pleural infection has usually shown a marked curative influence. Similar results are observed with dogs.
乙氢去甲奎宁 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-136429 | 乙氢去甲奎宁 | 522-60-1 | 25 mg | 780 |
| 2026-09-15 | HY-136429 | 乙氢去甲奎宁 | 522-60-1 | 10 mM * 1 mL in DMSO | 858 |
