L-Tryptophyl-L-glutaminyl-L-prolyl-L-prolyl-L-arginyl-L-alanyl-L-arginyl-L-isoleucine is a fibronectin adhesion-promoting peptide that promotes the adhesion, spreading, and migration of endothelial cells by reacting with heparin binding domains of cells. A synthetic peptide and a therapeutic agent for ischemia-?reperfusion.