Triazavirin
Triazavirin 性质
| 储存条件 | under inert gas (nitrogen or Argon) at 2-8°C |
|---|---|
| 溶解度 | 二甲基亚砜：125 mg/mL（436.76 mM） |
| 形态 | 固体 |
| 颜色 | 浅黄至黄色 |
| InChI | InChI=1S/C5H4N6O3S.Na.H2O.H/c1-15-5-6-4-8-7-2(11(13)14)3(12)10(4)9-5;;;/h1H3,(H,6,8,9);;1H2; |
| InChIKey | HSYOIVJKWAPORA-UHFFFAOYSA-N |
| SMILES | O=C1C(=NN=C2NC(SC)=NN12)N(=O)=O.[NaH].O |
Triazavirin 用途与合成方法
Nucleoside analogue; Influenza virus
The efficacy of Triazavirin against the tick-borne encephalitis virus is estimated in the sensitive cell culture. In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin ) by accumulation in the SKEV cell culture.
The therapeutic efficacy Triazavirin against experimental Forest-Spring encephalitis on albino mice is studied. The results shows that in high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed.
Triazavirin 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-19743 | Triazavirin | 928659-17-0 | 5mg | 500 |
| 2026-09-15 | HY-19743 | Triazavirin | 928659-17-0 | 10 mM * 1 mLin DMSO | 550 |
