CLEAR COLORLESS TO LIGHT YELLOW LIQUID
Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 4.7-fold.
ganglionic blocker, antihypertensive
1,2,2,6,6-Pentamethylpiperidine is used in the synthesis of BN-fused polycyclic aromatic molecules for potential application to electronic materials and apparatus. In addition, it is a catalyst for th
e chemoselective silylation of benzylic alcohols.
ChEBI: 1,2,2,6,6-pentamethylpiperidine is a member of piperidines.
The focal 1,8-naphthalimide fluorophores in the antennae were modified with 1,2,2,6,6-pentamethylpiperidine to improve their photostability.
Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.