B-HT 920 is a potent agonist of dopamine 2 (D2) receptors (Ki = 5.8 nM) that shows selectivity for D2 over D3 and D4 receptors. It has neuroprotective and regenerative effects in animal models of Parkinson’s disease. B-HT 920 is also an agonist of α2-adrenergic receptors and an antagonist of serotonin-3 (5-HT3; Ki = 0.35 μM) receptors.
B-HT 920 DIHYDROCHLORIDE is Light Yellow Solid
B-HT 920 DIHYDROCHLORIDE is an alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent
ChEBI: Talipexole dihydrochloride is an azepine.
Dopamine D 2 receptor agonist, α 2 -adrenoceptor agonist and 5-HT 3 receptor antagonist. Displays antiParkinsonian activity.