Description
B-HT 920 is a potent agonist of dopamine 2 (D
2) receptors (K
i = 5.8 nM) that shows selectivity for D
2 over D
3 and D
4 receptors. It has neuroprotective and regenerative effects in animal models of Parkinson’s disease. B-HT 920 is also an agonist of α
2-adrenergic receptors and an antagonist of serotonin-3 (5-HT
3; K
i = 0.35 μM) receptors.
References
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