Evernic acid is a secondary metabolite produced by some species of lichen that can bind to allosteric sites on the protein surface of FAS-II enzymes and produce antibacterial and antiplasmodial effects. It inhibits two key plasmodial FAS-II enzymes PfFabZ and PfFabI (IC50 = 10.7 and 36.1 μM, respectively) but shows low efficacy against the malaria parasite P. berghei (IC50 = 77.3 μM).
Propazine (Standard) is the analytical standard of Propazine. This product is intended for research and analytical applications. Propazine is a triazine herbicide that effectively manages broad-leaved weeds and annual grasses in sweet sorghum cultivation.
ChEBI: 2-hydroxy-4-[(2-hydroxy-4-methoxy-6-methylphenyl)-oxomethoxy]-6-methylbenzoic acid is a carbonyl compound.
[1] INA L. LAUINGER. Potential of Lichen Secondary Metabolites against Plasmodium Liver Stage Parasites with FAS-II as the Potential Target[J]. Journal of Natural Products , 2013, 76 6: 1064-1070. DOI:
10.1021/np400083k