Adjunct to diet and statin in hypertriglyceridaemia
Adjunct to secondary prevention after a MI
Drug interactions
Potentially hazardous interactions with other drugs
Anticoagulants: may increase bleeding time.
Metabolism
DHA and EPA are metabolised and oxidised in the
liver, which is the site of biosynthesis of n-3 fatty acid
intermediates, synthesizing VLDL that transport fatty
acids in the plasma to tissues.