(S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol is a useful intermediate for the synthesis of amino alcohols.
(S)-(-)-2-AMINO-3-METHYL-1,1-DIPHENYL-1-BUTANOL is prepared from valine methyl ester hydrochloride and excess Phenylmagnesium Bromide in 56% yield.
No special information available. In general, however, it is advisable that all reactions with this reagent be conducted in a well ventilated fume hood. Care should be exercised to avoid contact of this reagent and the derived oxazaborolidine catalyst with the eyes and skin.
