Vap press 3 mm Hg (20C). Soluble
in acetone, benzene, carbon tetrachloride, fuel oil,
toluene, xylene.
Isobenzan (telodrin) is a highly toxic organochloride insecticide. It was produced only in the period from 1958 to 1965 and its use has been since discontinued.[1] It is a persistent organic pollutant that can remain in soil for 2 to 7 years, and the biological half-life of isobenzan in human blood is estimated to be about 2.8 years.
ChEBI: Isobenzan is a member of oxolanes.
Isobenzan is commercially synthesised through a multi-step chlorination and cyclization process. The production begins with hexachlorocyclopentadiene, which undergoes a Diels-Alder reaction with a furan-based compound to form a bridged polycyclic intermediate. This intermediate is then subjected to extensive chlorination under controlled conditions to introduce eight chlorine atoms, resulting in the final compound.
Crystals. The technical product is a whitish to light-brown crystalline powder with a mild chemical odor. Used as an insecticide. Not registered as a pesticide in the U.S.
Chlorine is evolved when ISOBENZAN is heated above 410F. Avoid acids, certain metal salts, and catalytically active carriers. [EPA, 1998].
ISOBENZAN is highly toxic. It is absorbed by the skin as well as by the respiratory and gastrointestinal tract. Symptoms may last for a long time because the material is eliminated slowly; its half-life in human blood is 2.77 years.
Chlorine is evolved when ISOBENZAN is heated above 410F. Avoid acids, certain metal salts, and catalytically active carriers.
Broad-spectrum with contact and stomach activity. Thought to over stimulate the nervous system. GABA-gated chloride channel antagonist.
Poison by ingestion, skin contact,intraperitoneal, and intravenous routes. Questionablecarcinogen with experimental tumorigenic data. Used asan insecticide. When heated to decomposition it emitstoxic fumes of Clí.
