Basic information Safety Related Supplier

7-CHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID HCL

Basic information Safety Related Supplier
7-CHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID HCL Basic information
7-CHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID HCL Chemical Properties
  • Melting point:277-278 °C (decomp)
  • Boiling point:461.5±45.0 °C(Predicted)
  • Density 1.600±0.06 g/cm3(Predicted)
  • storage temp. Sealed in dry,Room Temperature
  • solubility 0.1 M NaOH: 13.7 mg/mL
  • form solid
  • pka0.90±0.30(Predicted)
  • color tan
  • CAS DataBase Reference18000-24-3(CAS DataBase Reference)
Safety Information
  • Hazard Codes Xi
  • Risk Statements 36/37/38
  • Safety Statements 26-36
  • WGK Germany 3
MSDS
7-CHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID HCL Usage And Synthesis
  • DefinitionChEBI: A quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the MDA receptor. It also prevents neurodegeneration produced by quinolinic acid.
  • Biological ActivityNMDA receptor antagonist acting at the glycine site. Potent competitive inhibitor of L-glutamate transport into synaptic vesicles. Also available as part of the NMDA Receptor - Glycine Site Tocriset™ .
7-CHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID HCL(18000-24-3)Related Product Information
7-CHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID HCLSupplierMore
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