5-Bromo-2,3-difluoro-1-nitrobenzene

5-Bromo-2,3-difluoro-1-nitrobenzene can be used as a synthesis precursor to prepare 4-(benzyloxy)-N'-(4-bromo-2-fluoro-6-nitrophenyl)benzhydrazide by reacting with 4-benzyloxybenzhydrazide in dry DMSO[1].

5-Bromo-2,3-difluoro-1-nitrobenzene can be prepared by the bromination of 2,3-difluoronitrobenzene with NBS in sulfuric acid with the addition of trifluoroacetic acid[1].

[1]Cigl, M., Pociecha, D., Jakubowski, R., Kapuściński, S., & Kaszyński, P. (2023). Paramagnetic Liquid Crystals With Close π–π Packing: The Effect of Blatter Radical Planarization on Behavior of Bent‐Core Mesogens. Chemistry – A European Journal, 29(15). https://doi.org/10.1002/chem.202203288