CP-122288, a highly potent inhibitor of neurogenic inflammation, can be used in migraine study[1].
References
[1] K I Roon, et al. No acute antimigraine efficacy of CP-122,288, a highly potent inhibitor of neurogenic inflammation: results of two randomized, double-blind, placebo-controlled clinical trials. Ann Neurol. 2000 Feb;47(2):238-41. PMID:10665496