Uralenol is a natural PTP1B inhibitor (IC50=21. 5 μM) from Broussonetia papyrifera. PTP1B have been shown to play a major role in the dephosphorylation of the insulin receptor in many cellular and biochemical studies[1].
Definition
ChEBI: Uralenol is a member of flavones.
References
[1] Chen RM, et al. Natural PTP1B inhibitors from Broussonetia papyrifera. Bioorg Med Chem Lett. 2002;12(23):3387-3390. DOI:10.1016/s0960-894x(02)00757-6
