Sulfamic acid, 4-[(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)amino]phenyl ester

Steroid sulfatase -IN-2 is an active steroid sulfatase (STS) inhibitor with an IC50 value of 109.5 nM. Steroid sulfatase-IN-2 can be used for the research of hormone-dependent cancers, such as estrogen-dependent breast and endometrial cancer[1].

[1] Mohammed I El-Gamal, et al. A new series of aryl sulfamate derivatives: Design, synthesis, and biological evaluation. Bioorg Med Chem. 2020 Apr 15;28(8):115406. DOI:10.1016/j.bmc.2020.115406