cloral betaine

Beta-Chlor,Mead Johnson,US,1963

Sedative-hypnotic.

An intimate mixture of betaine hydrate (67.5 g) and chloral hydrate (100 g) was warmed to ca. 60°C when an exothermic reaction occurred and the mixture became pasty. It was then stirred at 60°C for 30 minutes. The residue solidified on cooling and was crystallized from a small amount of water. The product separated in hard, colorless prisms of MP 122.5 to 124.5°C (corr).

Sedative