ChemicalBook Product Catalog API Digestive system drugs Antacid and Mucosal protective Drugs Tritiozine

Tritiozine

Chemical Properties

Toxicity

LD50 i.p. in mice: 2000 mg/kg (Pifferi, 1973)

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Animal Model:	female Sprague-Dawley rats and male beagle dogs^[1]
Dosage:	50 mg/kg (rats); 200 mg/kg or 50 mg/kg (dogs)
Administration:	i. p., single (rats); oral, single or i. v. (dogs)
Result:	Showed an apparent plasma half-life of about 2.5 h in rats and 1 h in dogs and rapidly metabolized yielding two metabolites and two conjugates.