1-O-HEXADECYL-2-O-ACETYL-SN-GLYCEROL

Product Name1-O-HEXADECYL-2-O-ACETYL-SN-GLYCEROL
CAS77133-35-8
MFC21H42O4
MW358.56
EINECS
MOL File77133-35-8.mol

Chemical Properties

storage temp.	-20°C
solubility	DMSO: 10 mg/ml; Ethanol: Miscible; PBS (pH 7.2): ~150 μg/ml
form	Waxy solid.

Usage And Synthesis

Uses

C16-02:0 DG or 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG) may be used to inhibit the formation of 1-O-acyl-NAS.

Uses

C16-02:0 DG or 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG) may be used to prevent 1-O-acyl-NAS formation.

Definition

ChEBI: 1-O-palmityl-2-acetyl-sn-glycerol is a 1-alkyl-2-acetylglycerol in which the 1-alkyl group is specified as palmityl (hexadecyl). It is a 1-alkyl-2-acetylglycerol and a 1-alkyl-2-acetyl-sn-glycerol. It is functionally related to an acetic acid.

General Description

C16-02:0 DG, also called as 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG), is an alkylacylglycerol and a bioactive lipid. Structurally, HAG contains primary alcohol group at the C3 position.

Biochem/physiol Actions

C16-02:0 DG or 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG) is a diacylglycerol (DAG) antagonist with a potential to inhibit protein kinase C (PKC) activity. It also has an ability to inhibit growth of human promyelocytic leukemia cell line HL-60. HAG serves as a precursor in the biosynthesis of platelet-activating factor.