EB 47 is a potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Poly(ADP-ribose) polymerases (PARPs) play a major role in cellular survival and maintenance of energy stores after genotoxic insult.
Biological Activity
Cell permeable: yes', 'Primary Target PARP-1', 'Product does not compete with ATP.', 'Reversible: no
