Propicillin was synthesized by a collaboration of Beecham Research Laboratories with Bristol-Myers Laboratories in 1961 starting with 6-aminopenicillanic acid. It is stable against gastric acid and shows three- to fourfold higher serum concentrations than phenoxymethyl-penicillin when administered orally. Its antibacterial spectrum and activity are almost the same as those of phenoxymethylpenicillin. Propicillin has been used for therapy of infections caused by Streptococcus, Staphylococcus, and Neisseria.
Propicillin, is a derivative of penicillin. Properties are similar to benzylpenicillin particularly used in streptococcal infections, not resistant to penicillinase.
ChEBI: Propicillin is a penicillin. It is a conjugate acid of a propicillin(1-).
