Fangchinoline is an isolate from Stephania Tetrandra that shows anti-cancer activity. It inhibits breast adenocarcinoma proliferation through apoptosis induction. In addition, it has been shown to inhibit HIV-Type 1 replication.
Thalictrum rugosum Ait also contains this alkaloid which is dextrorotatory with
[o:lbo + 128° (MeOH). The ultraviolet spectrum of this base consists of a single
absorption maximum at 283 flI/J..
Fangchinoline is an isolate from Stephania Tetrandra that shows anti-cancer activity. It inhibits breast adenocarcinoma proliferation through apoptosis induction. In addition, it has been shown to inhibit HIV-Type 1 replication.
Mitscher et al., Chem. Commun., 589 (1971)
