NSC 625987 is a cyclin-dependent kinase (cdk) 4 inhibitor.
ChEBI: 1,4-dimethoxy-10H-acridine-9-thione is a member of acridines.
Cyclin-dependent kinase (cdk) 4 inhibitor (IC 50 = 0.2 μ M at cdk4/cyclin D1). Displays > 500-fold selectivity over cdk2 (IC 50 > 100 μ M for cdc2/cyclin A, cdk2/cyclin A and cdk2/cyclin E).
