N-DBCO-N-bis(PEG2-acid) is a branched click chemistry linker containing a DBCO and two PEG2-acid chains attached to a central nitrogen group. The DBCO group participates in copper-free Click Chemistry reactions with azide. Carboxylic acid (CO2H) allows for reactions with primary amine groups using activators such as EDC or HATU to form a stable bond.
N-DBCO-N-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-DBCO-N-bis(PEG2-C2-acid) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
