Oxiracetam, like piracetam and aniracetam, is a supplement belonging to the racetam family. It is a brain development supplement that increases attention span, memory, and mental energy. However, the proven effects of the drug are limited to beneficial effects that lead to higher scores in tests for logical performance, attention, concentration, memory and spatial orientation. At present, Oxiracetam is not approved by Food and Drug Administration for any medical use in the United States.
- Melting point:165-168 °C
- Boiling point:494.6±40.0 °C(Predicted)
- Density 1.416
- storage temp. 2-8°C
- Merck 14,6942
- CAS DataBase Reference62613-82-5(CAS DataBase Reference)
- Indications and UsageOxiracetam, Piracetam and Aniracetam, are three commonly used brain metabolism-improving drugs and are pyrrolidone derivatives. They were developed in 1974 by the Italian company ICF and went on sale in 1987.
Oxiracetam is a Piracetam derivative and excites the central nervous system, promotes brain metabolism, significantly increases and promotes memory retention, and effectively treats senile memory and mental decline. It is used to treat brain dysfunction psychiatric syndrome and mental disorders. It can improve the memory and learning abilities of patients with senile dementia or memory disorders. It is suitable for treating neural dysfunction, memory disorder and intelligence disorders caused by brain damage. It can also be used as a recovery treatment for neurosis, brain trauma, encephalitis, and other brain diseases. Oxiracetam’s greatest advantage is that it is very soluble in water, making it suitable for injection. Research shows that Oxiracetam has higher pharmacological activity and significant curative effects compared to Piracetam.
- Mechanisms of ActionOxiracetam’s mechanisms of action are similar to those of Piracetam. It promotes the binding of phosphorylcholine and phosphoethanolamine, increases the ratio of ATP/ADP in the brain, and increases the binding of protein with nucleic acids in the brain, thus improving the memory and learning ability of patients with senile dementia and memory disorder.
- PharmacokineticsAfter intake, most of the drug will not accumulate in the body and will be excreted through urine in its original form. It is well-absorbed and well-tolerated.
- Clinical ResearchAnimal trials showed that in all types of behavioral experiments, Oxiracetam can improve memory retention and learning ability, reduce brain shocks’ damage on memory, and prevent the learning abilities of rats suffering from spontaneous hypertensive cerebrovascular injury from decreasing. It can also increase acetylcholine circulation in rats’ skin and hippocampus, thus increasing affinity for choline uptake.
- DescriptionOxiracetam is a 4-hydroxy analog of piracetam, reportedly useful in relieving the symptoms of cerebral insufficiency in the elderly.
- Chemical PropertiesWhie Solid
- OriginatorISF (Italy)
- UsesNootropic. Analog of Piracetam with psychostimulant activity.
- brand nameNeuromet
- Purification MethodsThis nootropic (Alzheimer) drug is purified by recrystallisation from MeOH or aqueous Me2CO and dried in vacuo. [NMR, IR: Pifferi & Pinza Farmaco Ed Sci 32 602 1977, Banfi et al. Farmaco Ed Sci 39 16 1984, Gouilaev & Senning Brain Research Rev 19 180 1994.]
- oxiracetaM related substance ISF3886 Omeprazole Mecobalamin Pramiracetam Aniracetam Nefiracetam ILOPERIDONE Paliperidone Piracetam Oxiracetam 4-Hydroxy-2-pyrrolidone Pyrrole (R) - Oxiracetam 2-aminoacetamide hydrochloride (intermediate of oxiracetam) Oxiracetam(Neuromet) (S)-OXIRACETAM 1-(2-aminoethyl)pyrrolidin-2-one
- Company Name:JX NUTRITIONAL CHEMICAL CO., LIMITED Gold
- Products Intro:Product Name:Oxiracetam
Purity:99% HPLC Package:25KG;5KG;1KG
- Company Name:Jinan Jason Pharmaceutical Co., Ltd. Gold
- Tel:0531-82956131 15069164249
- Products Intro:Product Name:4-Hydroxy-2-oxopyrrolidine-N-acetamide
- Company Name:PharmaResources (Kaiyuan) Co., Ltd. Gold
- Tel:13671531211 021-50720100-
- Products Intro:Product Name:Oxiracetam
Purity:99% Package:1kg, 100kg
- Company Name:J & K SCIENTIFIC LTD.
- Tel:400-666-7788 010-82848833-
- Products Intro:Product Name:Oxiracetam, 95%
- Company Name:Chembest Research Laboratories Limited
- Products Intro:Product Name:OxiracetaM