Mal-PEG8-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media.
Mal-PEG8-NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Mal-PEG8-NHS ester (CAS 2055033-05-9) is a high-purity, PEG-based PROTAC linker suitable for the synthesis of PROTACs. It has a molecular weight of 618.63 and appears as a colourless to pale yellow viscous liquid or a low-melting-point waxy solid at room temperature.