BD-1047盐酸盐
BD-1047盐酸盐 性质
储存条件 | Inert atmosphere,2-8°C |
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溶解度 | 在水中的溶解度>5mg/mL |
形态 | 粉末 |
颜色 | 白色 |
稳定性 | 自购买之日起,稳定期为 1 年。 其DMSO 或蒸馏水中的溶液可在 -20°C 下保存长达 3 个月。 |
BD-1047盐酸盐 用途与合成方法
Target | Value |
σ1 receptor
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BD-1047 (dihydrobromide) prevents that Cutamesine reduces the cell death rate induced by light exposure in murine photoreceptor-derived 661w cells.
BD-1047 (dihydrobromide) attenuates that Cutamesine reduces the mitochondrial damage and the elevated level of caspase 3/7 activity.
BD-1047 (dihydrobromide) (1-10 mg/kg; i.p.) decreases the Apomorphine (APO)-induced climbing behavior at the dose of 10 mg/kg in mice.
BD-1047 (dihydrobromide) counteracts the antidepressant-like effect induced by co-administration of pramipexole and sertraline (but not pramipexole and fluoxetine).
BD-1047 (dihydrobromide) reduces the increasing expression of pNR1, and reverses the Sig-1 R agonists potentiated NMDA-induced pain behaviour and pNR1 immunoreactivity.
Animal Model: | Male Albino Swiss mice (50 days old, 25–28 g) |
Dosage: | 1 mg/kg, 3 mg/kg, 10 mg/kg |
Administration: | Intraperitoneal injection |
Result: | Decreased the APO-induced climbing at the dose of 10 mg/kg in mice. |
BD-1047盐酸盐 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024-11-08 | S0106 | BD-1047盐酸盐 | 138356-21-5 | 5mg | 753.46 |
2024-11-08 | S0106 | BD-1047盐酸盐 | 138356-21-5 | 25mg | 2024.47 |