4-[1-Chloro-2-(methylamino)ethyl]phenyl Acetate Hydrochloride

Glucocorticoid receptor activator 1 (compound A) is a phenyl aziridine precursor and an activator of the glucocorticoid receptor (GR). Glucocorticoid receptor activator 1 down-modulates TNF-induced pro-inflammatory gene expression by activating GR and can be utilized in inflammation research[1].

[1] De Bosscher K, et al. A fully dissociated compound of plant origin for inflammatory gene repression. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15827-32. DOI:10.1073/pnas.0505554102