A-794282 is a compound with analgesic activity and is a selective mGlu1 receptor antagonist that significantly reduces pain behaviors in a postoperative pain model, but motor side effects may occur at higher doses.
IC 50
mGluR1
References
[1] Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats DOI:10.1016/j.ejphar.2007.09.047 [2] [Research progress of selective mGluR1 antagonists] PMID:22242445
